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- $Unique_ID{BRK03784}
- $Pretitle{}
- $Title{Granuloma Annulare}
- $Subject{Granuloma Annulare Lichen Annularis Ringed Eruption Eruptive
- Xanthoma}
- $Volume{}
- $Log{}
-
- Copyright (C) 1987, 1989 National Organization for Rare Disorders, Inc.
-
- 456:
- Granuloma Annulare
-
- ** IMPORTANT **
- It is possible the main title of the article (Granuloma Annulare) is not
- the name you expected. Please check the SYNONYMS listing on the next page
- to find alternate names, disorder subdivisions, and related disorders
- covered by this article.
-
- Synonyms
-
- Lichen Annularis
- Ringed Eruption
-
- Information on the following disorder may be found in the Related
- Disorders section of this report:
-
- Eruptive Xanthoma
-
- General Discussion
-
- ** REMINDER **
- The information contained in the Rare Disease Database is provided for
- educational purposes only. It should not be used for diagnostic or treatment
- purposes. If you wish to obtain more information about this disorder, please
- contact your personal physician and/or the agencies listed in the "Resources"
- section of this report.
-
- Granuloma Annulare is a benign, chronic skin disorder characterized by
- elevated spots (papules) or nodules that form a ring with normal or slightly
- depressed skin in the center.
-
- Symptoms
-
- Granuloma annulare is characterized by small, firm, yellowish or skin-colored
- nodules arranged in a ring on the skin. They are most common on the back of
- the hands and feet, the ankles, knees, or elbows. The disorder can be
- chronic with possible remissions and/or recurrence of spots.
-
- Causes
-
- The exact cause of Granuloma Annulare (GA) is not known. The disseminated
- type of the disorder which affects large areas of the body may be associated
- with Diabetes Mellitus. Granuloma Annulare may also be a complication of
- pseudorheumatoid nodules or shingles (Herpes Zoster). Some forms of GA tend
- to run in families (familial), but the exact mode of inheritance has not yet
- been determined. (For more information on the above disorders, chooses
- "Diabetes Mellitus" and "Herpes Zoster" as your search terms in the Rare
- Disease Database.
-
- Affected Population
-
- Granuloma Annulare is more common in females than in males. The disorder may
- occur in children and adults.
-
- Related Disorders
-
- Symptoms of the following disorder can resemble those of Granuloma Annulare.
- They may be useful for a differential diagnosis:
-
- Eruptive Xanthoma is characterized by clusters of small yellow or
- yellowish-brown elevated spots over the entire body. The clusters may be
- encircled by a red ring. This disorder may be distinguished microscopically
- from Granuloma Annulare by the different coloring of its histiocyte cells.
-
- Therapies: Standard
-
- Usually the eruptions of Granuloma Annulare disappear without treatment
- (spontaneous remission). Treatment for chronic forms of the disorder include
- the antibacterial drug dapsone, and isotretinoin, which is the synthetic form
- of retinoic acid (related to vitamin A).
-
- Therapies: Investigational
-
- This disease entry is based upon medical information available through
- October 1987. Since NORD's resources are limited, it is not possible to keep
- every entry in the Rare Disease Database completely current and accurate.
- Please check with the agencies listed in the Resources section for the most
- current information about this disorder.
-
- Resources
-
- For more information on Granuloma Annulare, please contact:
-
- National Organization for Rare Disorders (NORD)
- P.O. Box 8923
- New Fairfield, CT 06812-1783
- (203) 746-6518
-
- The National Arthritis and Musculoskeletal and Skin Diseases Information
- Clearinghouse
- Box AMS
- Bethesda, MD 20892
- (301) 495-4484
-
- References
-
- SULFONE TREATMENT OF GRANULOMA ANNULARE: A. Steiner, et al.; Journal Am Acad
- Dermatol (December 1985: issue 13(6)). Pp. 1004-1008.
-
- RESOLUTION OF DISSEMINATED GRANULOMA ANNULARE FOLLOWING ISOTRETINOIN
- THERAPY: S.M. Schleicher, et al.; Cutis (August 1985: issue 36(2)). Pp.
- 147-148.
-
- LOCALIZED GRANULOMA ANNULARE IS ASSOCIATED WITH INSULIN-DEPENDENT
- DIABETES MELLITUS: M.F. Muhlemann, et al.; British Journal Dermatol
- (September 1984: issue 111(3)). Pp. 325-329.
-
-